Chlorophyll Derivatives from Marine Cyanobacteria with Lipid-Reducing Activities

Regulatory elements of marine cyanobacteria.

The free-living, oxyphototroph bacteria of the group of Prochlorococcus populate widely the oceans. Genomic information of nine marine cyanobacteria was used to predict signals essential for regulation. We implemented a pipeline that automatically calculates BLASTp alignments of query genomes, selects a representative subset of orthologs and predicts motifs conserved in their upstream sequences...

Cycloartanes from Oxyanthus pallidus and derivatives with analgesic activities

BACKGROUND The leaves of Oxyanthus pallidus Hiern (Rubiaceae) are extensively used in the west region of Cameroon as analgesic. These leaves are rich in cycloartanes, a subclass of triterpenes known to possess analgesic and anti-inflammatory properties. The present study aimed at evaluating the analgesic properties of three cycloartanes isolated from Oxyanthus pallidus leaves as well as their a...

Evolutionary radiation of lanthipeptides in marine cyanobacteria.

Lanthipeptides are ribosomally derived peptide secondary metabolites that undergo extensive posttranslational modification. Prochlorosins are a group of lanthipeptides produced by certain strains of the ubiquitous marine picocyanobacteria Prochlorococcus and Synechococcus Unlike other lanthipeptide-producing bacteria, picocyanobacteria use an unprecedented mechanism of substrate promiscuity for...

Marine diazotrophic cyanobacteria: Out of the blue

Cyanobacteria are now recognized as the primary nitrogen-fixing (diazotrophic) microorganisms in the oceans as contributing significantly to the biogeochemistry of the global nitrogen cycle. The evolution of a remarkable range of morphologies and metabolic capacities has led to a behavioural versatility that helps them to proliferate and combat nutrient limitations in oceanic ecosystems. Advanc...

Biodiversity in Chemically Rich Tropical Marine Cyanobacteria